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WAVE PROTEINS
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DeCS
Descriptor
English
:
Wiskott-Aldrich Syndrome Protein Family
Descriptor
Spanish
:
Familia de Proteínas del Síndrome de Wiskott-Aldrich
Descriptor
Portuguese
:
Família de Proteínas da Síndrome de Wiskott-Aldrich
Synonyms
English
:
WAS Protein Family
WASP-Family Verprolin Homologous Proteins
WAVE Proteins
Tree Number:
D05.750.078.730.912
D12.776.220.525.912
Definition
English
:
A
family
of
microfilament proteins
whose name derives from the fact that mutations in members of this protein
family
have been associated with
WISKOTT-ALDRICH SYNDROME
. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
Indexing Annotation
English
:
WISKOTT-ALDRICH SYNDROME PROTEIN
and
WISKOTT-ALDRICH SYNDROME PROTEIN
, NEURONAL are also available
History Note
English
:
2006(1999)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50563
Unique Identifier:
D051300
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS